That pharmaceuticals place high demands on their production is hardly surprising. The end-product must be always safe and effective, and waste of precious API 's must be avoided wherever possible.
For example, during production in the pharmaceutical industry, metering pumps are used to dose additives very accurately. These pumps must meet high standards. This is vital to ensure that drug production is safe and effective. Gear pumps are then a logical choice.
One of the advantages of gear pumps is their precision, which is very important for the quality of the final product. This is because the amount of liquid pumped can be controlled and adjusted to the specific requirements of a production process. Wasting expensive ingredients is therefore a thing of the past. Moreover, gear pumps are characterised by continuous, pulsation-free dosing and low shear stress. Two more important contributions to your quality!
As gear pumps are configured specifically for the application, they are highly reliable and durable. The high-quality and possibly polished (Ra < 0.8) materials are resistant to corrosion and wear. This makes them suitable for use in demanding environments, such as clean rooms.
Due to the chemical character of additives, it is often necessary for pumps to be leak-proof. Magnetically coupled gear pumps are hermetically sealed. The shaft seals have given way to a magnetic bushing with static seals that hermetically seal the pump. This way, no leakage can occur!
To meet the GMP guidelines to which pharma must conform, gear pumps are available that are either SIP- or CIP-cleanable. Designed to meet the highest hygiene and quality requirements, they can be thoroughly cleaned without dismantling.
Inspection documentation is made available for the wetted parts:
For the metal parts, material certificates type 3.1 and the declaration of conformity 2.1 (DIN EN 10204:2005) are supplied. Including ATEX certification if applicable.
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Suurmond have added a new product range to their portfolio for the food and pharma industries; the MAAG PFS series for hot-melt extrusion and micro pelletizing. With the advanced technologies by MAAG, a new era has begun when it comes to making high quality solid dosage forms for pharmaceutical and food applications.
MAAG’s technologies produce homogenous, consistent micro pellet sizes, ensure continuous manufacturing in simplified processes, avoids the creation of dust during the process and require no grinding! The complete PFS range complies with pharma and food directives!
Pellets are neither powder nor granules; they are characterized by a defined shape and a very narrow particle size distribution. This allows a very wide range of applications that integrate active substances such as tableting, and capsule filling in the pharmaceutical industry, and sweetener and gum base in the food industry. Since no grinding is used in the process, the structure and the effectiveness of active substances remain unaffected.
Hot-melt extrusion (HME) has been revealed as a successful technology for a large spectrum of applications in the pharmaceutical industry, with proven robustness for numerous drug delivery systems. With HME, even the processing of poorly soluble carrier/active substance combinations, no longer poses a major problem in the pharmaceutical industry.
Some of the most well-known applications are for taste-masking of drugs, solubility enhancement of poorly water-soluble compounds, controlled, extended, sustained and targeted drug delivery.
The MAAG extrex® PFS gear pumps are specially designed for applications in the pharmaceutical industries. Such applications require specific design characteristics: high discharge pressure capability, constant throughput, gentle conveying, and narrow temperature ranges. In such an environment, the proven extrex® gear pumps unfold their full potential.
MAAG offer different types of micro pelletizers, meeting precisely the demands of the pharmaceutical industry with its specially developed pelletizing systems. The innovative pelletizing technology results in particles of uniform shape and size for optimal direct further processing.
The various types of pelletizing systems are all dedicated to a certain type of formulation or process such as:
Check the video!
Automated analysis devices are the essential basis for extensive test capacities for the corona virus. Through parallel and faster processes, automation significantly increases the number of tests, saves manpower and ensures process reliability.
For sample preparation for SARS-CoV-2, a few microliters of a solution of chemicals and enzymes are dosed. Micro annular gear pumps of the low-pressure series from HNP Mikrosysteme perform this demanding task with highest precision and process reliability. The minimum dosing quantity is 0.25 µl, the pumps have a very small footprint and can be easily integrated into control systems. Fully automated analysis devices can contain up to sixteen dosing pumps and can handle up to 4,000 samples in 24 hours.
Micro dosing pumps are also used in research on vaccines and therapies against COVID-19. Every development step in research institutes at universities, in international pharmaceutical companies or in start-ups worldwide is accompanied by numerous laboratory tests. This is a mammoth task, which is also carried out automatically.
HNPM micro pumps of various series, such as hermetically inert pumps, are used in the production of vaccines. From diagnostics and research to future vaccine production, micro pumps can be used in the fight against COVID-19. In applications requiring small and very small quantities of liquids delivered with high precision, mzr-pumps by HNP Mikrosysteme provide accurate service and ensure process reliability.
HNP Mikrosysteme GmbH, located in Germany, develops, manufactures and markets pumps and systems worldwide which deliver small amounts of liquids fast and accurately. Besides several applications in plant engineering, chemical processing and pharmaceutical processing,mzr-pumps are used in the field of life-science and analytical instrumentation.
HNP Mikrosysteme is represented by Suurmond in Belgium and The Netherlands.
New MAAG industrial gear pumps for precise dosing and conveyance. For industrial applications the processed medias vary widely from corrosive and abrasive media, to applications with high (differential) pressures, high viscosities, and high temperatures. With the new MAAG innovations, pump types dosixTM and flexinoxTM , Suurmond further extends her portfolio and can herewith satisfy the demand for precise dosing and conveying units even better for a wide range of diversified media.
Due to the chemical properties of the conveyed media, the quality requirements for industrial applications are very stringent and diversified. Thanks to their chemical resistance the MAAG dosixTM and MAAG flexinoxTM gear pumps are used for different chemicals involving highly pure, corrosive, viscous or very hot media, e.g. acids, solvents, molten sulphur, and flavours or fragrances but also for food and pharma processes.
The housing cover of both MAAG dosixTM and MAAG flexinoxTM consists of a three-piece configuration that facilitates maintenance and the replacement of internal parts, i.e. gears and bearings.
The MAAG dosixTM is corrosion resistant and electrically heatable especially designed for small throughputs. The superior dosing precision of the pump makes it an ideal solution for applications such as flavours and fragrances that require the accurate dosing of low viscosity scent and aroma components. The new dosixTM is available in five different sizes.
The MAAG flexinoxTM gear pumps are also corrosion resistant and can be heated, either electrically or by fluid. The flow rates are higher compared to the dosixTM and the application range is extended to resins and various plastics, e.g. precursors of carbon fibres. The new MAAG flexinoxTM is available in four different sizes.
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